I would argue that those sanctions, if general, shouldn’t include necessities like food or medicine. Also, I feel that sanctions against specific figures in the government might be relatively effective (many countries are doing this already). Make it difficult to enjoy the fortune they stole from their people.

I also don’t like the idea of sanctions that aren’t based on specific/ongoing actions, but the existence of a certain government/regime, though I see where you are coming from.

I would also still argue that the Russian people chose that government, back when they did choose, because they didn’t see many other options, and keeping them in perpetual destitution long term isn’t likely to change that.