Yes, it is definitely possible. How it is achieved largely depends on the desktop environment pr window manager you use.
I use the meta key largely for things related to windows and workspaces. I use the capslock key as the compose key. And, the right alt key for alternative characters. Additionally, there is Ibus for typing a variety of scripts and languages.
I set up Mint on my parent’s PC a couple of years ago, and the amount of support I have had to provide has dropped to basically zero.